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Say Goodbye to Fillings: Scientists Are Growing Real Teeth in the Lab

Micaela Roberts by Micaela Roberts
April 18, 2025
in Science Tech
21 14
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Say Goodbye to Fillings: Scientists Are Growing Real Teeth in the Lab

Image Credit: King's College London, Dr Ana Angelova Volponi holding a tooth

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  1. Breakthrough at King’s College London enables lab-grown teeth using patient’s own cells, offering a natural alternative to fillings and implants.
  2. New bioengineered material replicates tooth development environment, allowing cells to communicate and trigger natural tooth formation.
  3. Future treatments may include growing teeth directly in the mouth or in the lab for implantation, advancing the field of regenerative dental care.

In a pioneering development that could transform dental care, researchers at King’s College London have made significant progress toward growing teeth in the lab, offering a potential natural alternative to traditional fillings and implants. The innovation focuses on regenerating teeth using a patient’s own cells, a method that could allow new teeth to develop and integrate seamlessly with the jaw.

Unlike fillings or implants, which are fixed and often fail to replicate the full function of natural teeth, lab-grown teeth have the potential to repair themselves and adapt over time. This approach could address long-standing issues with current dental treatments, such as weakened tooth structures, limited lifespans of materials, and complications from invasive procedures.

The breakthrough came as part of a long-term collaboration between King’s College London and Imperial College London. Researchers developed a bioengineered material that mimics the natural environment surrounding tooth cells. This matrix allows cells to communicate effectively, sending signals that trigger the process of tooth formation—a mechanism similar to how teeth develop in the body.

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Now that scientists have successfully replicated the early stages of tooth growth in the lab, the next challenge is how to apply this technology to human patients. Two potential methods are being explored: transplanting early-stage tooth cells directly into the mouth or growing a complete tooth in the lab before implantation.

This research forms part of the broader field of regenerative medicine, which seeks to replace or repair body parts using natural biological processes. The findings from King’s College London not only represent a major advancement in dental science but also point to a future where lost or damaged teeth could be replaced with fully functional, living alternatives—eliminating the need for artificial substitutes altogether.

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